Isn’t this the age of information overload? A good reference book is invaluable to your engineering library (and expertise). We gathered this list of the best literature on powder and bulk solids to help you find your way through the reference jungle.
Whether you acquire them as hardcover or get your knowledge from ebooks, they are a must for your bookshelf.
Fundamentals of Multiphase Flow, C. E. Brennen, Cambridge University Press, 2005
Targeted to graduate students as well as cutting-edge researchers dealing with multiphase flow fundamentals, this reference book offers basic concepts of a broad spectrum. It does not detail any one multiphase flow or technological context, but references are included where appropriate.
Contact Mechanics, K. L. Johnson, Cambridge University Press, 1985
This treatise discusses stresses and deformation of solid bodies in contact with each other, along curved surfaces that touch initially at a point or along a line. The author reviews theory development, the influence of friction, topographical surface roughness, and contact mechanics. A portion of the book deals with sliding or rolling contact and collision.
Predictive Modeling of Pharmaceutical Unit Operations, P. Pandey & R. Bharadwaj, Woodhead Publishing, 2016
This book focuses on modeling and simulation tools pertinent to drug product manufacturing, especially those that can result in significant process improvements and cost savings. The author includes case studies, modeling principles, the role of modeling in manufacturing quality risk management, and modeling applications for continuous manufacturing and biologics.
Pharmaceutical Process Engineering, Anthony J. Hickey & David Ganderton, CRC Press, 2016
Providing step-by-step methods of drug production, insight into unit operations, and key pharmaceutical engineering concepts, this guide can help to improve communication among pharmaceutical professionals. It covers basic principles so scientists can easily convert bulk products into patient-ready dosage forms. The author includes information about recent advances, quality by design, mathematical/statistical approaches to experimental design, computer-aided design, and process analytical technology.
Pharmaceutical Process Scale-Up, Michael Levin, Marcel Dekker, 2001
This book details theory and practice of transferring pharmaceutical processes from laboratory-scale to pilot-plant and production-scale, reflecting rapid changes in the field. Drawing on the experience of contributing researchers, the book employs dimensional analysis as a unified scientific approach to quantify similar processes on different scales. Topics include
tableting scale-up and compaction, regulatory appendices, risk evaluation, and validation.
Mechanics of Inhaled Pharmaceutical Aerosols, W. H. Finlay, Academic Press, 2001
This book provides in-depth information on common aerosol-drug delivery devices, including nebulizers, dry powder inhalers and propellant metered-dose inhalers. The author details aerosol behavior in the respiratory tract (including evaporating and condensing droplets) as well as lung geometry, inhalation patterns and fluid mechanics.
Handbook of Industrial Mixing: Science and Practice, Edward L. Paul, Victor A. Atiemo-Obeng & Suzanne M. Kresta, Wiley-Interscience, 2003
The authors detail the trade-offs among various mixers pertinent to their specific applications: gear, top-entry, side-entry, bottom-entry, on-line and submerged mixers. The book contains a CD that shows mixers in action along with a usage overview.
Principles of Powder Technology, M. J. Rhodes, Wiley, 1990
This reference presents the fundamental engineering properties of materials that are essential to design and operation of industrial equipment and processes. As industry calls for greater expertise in this field, expert contributors offer data about problems involved in handling massive solids, gases and liquids.
Theory and Practice of Industrial Pharmacy, Leon Lachman, Herbert A. Lieberman & Joseph L. Kanig, Lea & Febiger, 1976
This is a comprehensive book for both pharmacy students and seasoned practitioners. New editions have kept pace with the changes in pharmacy curricula, particularly industrial pharmacy. By presenting the topics in layers from basics to in-depth discussions, the text enables easy conception of a-to-z of product development.
Particle‒Particle Adhesion in Pharmaceutical Powder Handling, Fridrun Podczeck, Imperial College,1998
This book describes the physical principles of adhesion between particles and surfaces, as they relate to pharmaceutical processes involved in the manufacture of solid dosage forms such as powders, granules, tablets and dry powder inhalations. The author includes information on solid-surface physical properties, friction theory, techniques for measuring particle adhesion, and fracture mechanical properties of powders.
Computational Granular Dynamics: Models and Algorithms, Thorsten Pöschel & Thomas Schwager, Springer, 2005
This introduction to applying numerical methods to granular-particle systems offers a general understanding of the subject rather than a presentation of numerical algorithms advances. While the book focuses more on models than on the physics of granular material, the authors present many applications to real systems.
Powder Technology Handbook, Koichi Iinoya, Keishi Gotoh & Ko Higashitani, Marcel Dekker, 1990
This handbook serves as a comprehensive guide to powder technology and the fundamental engineering processes of particulates. Its content on powder technologies in gas and liquid phases extends from particles and powders to powder beds and from basic problems to actual applications. Recent editions incorporate significant field advances.
Constitutive Modelling of Granular Materials, Dimitrios Kolymbas, Springer, 2000
Because today’s granular-materials mechanical behavior models are complex and, thus, difficult to compare, this book was designed to evaluate methods and encourage further research activities for soils and other granulates (such as sugar, wheat, coal, pellets). The reference presents state-of the-art contributions from leading finite element method specialists.
Advanced Pharmaceutical Solids, Jens T. Carstensen, CRC Press, 2000
This extensive reference explores principles, instrumentation, processes and programs of pharmaceutical solid science. It also covers new aspects related to one-component systems, micromeritics, polymorphism, solid-state stability, cohesion, powder flow, blending, single-unit sustained release, tablet coating and much more. The most recent edition is essential for pharmacists, scientists, chemists and students.
Particle Size Measurement, Terence Allen, Chapman and Hall, 1968
This edition reflects the change in industry from using nearly exclusive fluid analysis to applying powder characterization for in-process size analysis. Its themes are sampling, particle size measurement, surface area and pore-size determination. It includes information about on-line analysis, data extraction, and the latest instrumentation (including equipment, literature survey and manufacturer/supplier list).
Dynamics of Fine Powders, K. Rietema, Springer, 1991
The author explores particle and powder characteristics, mechanics of powders at rest, theoretical derivation of inter-particle forces, and two-phase systems. The book also discusses equations of motion, stability and perturbations, experiments with homogeneous fluidization, models of expanded powders, rheology of fluidized powders, fluidization in practice, and powder handling.
Of course, you won’t be reading these guides cover to cover. But they will be easily accessible, on your bookshelf (or cloud), when you need them. The biggest advantage of such reference books is that when you follow the guidelines and strategies, you gain added insight into your design or process while saving time and costs.
And that is where we step in. Scientists across the powder processing spectrum can leverage Rocky DEM state-of-the-art simulation tools to understand, optimize and scale their processes. Our unique discrete element modeling platform enables you to computationally analyze your process by mapping the dynamic interplay of process, material and geometric variables.